Acoerela
The World's first bilayer-spanning dyes

Acoerela Dyes are highly water-soluble and do not form micelles or nanoparticles when reconstituted in aqueous buffer unlike other dyes.  They are incredibly stable and only fluoresce when bound to the lipid bilayer.

Suitable for Exosomes, Extracellular Vesicles, Bacteria Gram Staining and Tumour Tracking

Aco-800™ | Aco-600™ | Aco-490™ | Aco-430

View our Acoerela Products

  • Select options This product has multiple variants. The options may be chosen on the product page
    $150.00$2,250.00 plus GST
  • Select options This product has multiple variants. The options may be chosen on the product page
    $150.00$2,250.00 plus GST
  • Select options This product has multiple variants. The options may be chosen on the product page
    $150.00$2,250.00 plus GST
  • Select options This product has multiple variants. The options may be chosen on the product page
    $150.00$2,250.00 plus GST
  • Select options This product has multiple variants. The options may be chosen on the product page
    $450.00 plus GST
Highly Stable

Traditional lipophilic dyes attach to the lipid bilayer in a hairpin style which tends to be unstable. These often detach and end up labelling other membrane-based targets leading to false positives.

Acoerela Dyes span the entire bilayer making them highly stable, minimising false positives.

"Light On" Mechanism

Acoerela dyes are characterised by a high quantum yield (>25%), but this increase in fluroescence is only observed when the dyes are bound to their target.

The change in hydrophobicity of the environment surrounding the dyes when they are bound underlies the "Light on" mechanism.

No Micelle Formation

Acoerela dyes are highly water-soluble and do not form micelles or nanoparticles, when reconstituted in aqueous solution.


Acoerela Dyes promise a low rate of false positives for accurate and reliable detection of exosomes and extracellular vesicles.

Gram-staining Bacteria

Extracellular Vesicles

Tumour Tracking

Why Choose Acoerela?

Fluorogenic

Acoerela dyes are characterized by a high quantum yield (>25%). The significant increase in fluorescence is only observed when the dyes are bound to their target, in which there is change in the hydrophobicity of the environment surrounding the dyes. The stark difference in emission profiles between bound and unbound dyes underlie the “light on” mechanism.​ ​

Diverse color options

The current chromophore platform of Acoerela dyes allows us to derive up to 3 different colors

and we are expanding on the excitation/emission profiles of these dyes to enable more multiplexing possibilities in different applications.

Water soluble

Acoerela Dyes are highly water soluble and do not form micelles or nanoparticles when reconstituted in aqueous buffer, unlike that of the family of PKH26, DiR and DiD dyes which will give rise to false positives in flow cytometry analysis of exosomes.
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