
We specialize in providing high quality recombinant Fc receptors in bulk quantities for biomedical R&D.
Gamma Proteins is the Fc receptor specialist, supplying recombinant proteins in two different categories: Fcγ receptors and FcRn. Explore the links below for more information on each product category, including the range of unconjugated and biotinylated proteins that are available. Alternatively for a full product list use the table below which can be filtered to find the specific product(s) to meet your requirements

Fcγ Receptors
Fc gamma receptors (FcgR or FcγR) are of most interest in therapeutic antibody development as the majority of antibodies or related molecules in development are of the IgG subclass. For this reason, Gamma Proteins focuses on the supply of high-quality Fc gamma receptors in unconjugated or biotinylated formats.
-
- Select options This product has multiple variants. The options may be chosen on the product page
$1,200.00 – $4,800.00 plus GSTRated 0 out of 5 -
- Select options This product has multiple variants. The options may be chosen on the product page
-
- Select options This product has multiple variants. The options may be chosen on the product page
-
- Select options This product has multiple variants. The options may be chosen on the product page

FcRn
FcRn binds IgG and albumin. These two proteins owe their long half-life to this interaction. The functions of FcRn are determined by whether IgG is a single monomeric molecule or an immune complex. As an immune complex FcRn has been shown to regulate the immune response as well as processing and presentation of antigens within the immune complex.
-
- Select options This product has multiple variants. The options may be chosen on the product page
-
- Select options This product has multiple variants. The options may be chosen on the product page
$1,500.00 – $6,000.00 plus GSTRated 0 out of 5 -
- Select options This product has multiple variants. The options may be chosen on the product page
-
- Select options This product has multiple variants. The options may be chosen on the product page

The mammalian immune system has evolved to defend organisms against pathogens by layering the specificity of the adaptive immunity on top of the ancestral innate immunity. It is Fc receptors that act as the bridge between the adaptive and innate immunity, bringing the fire power of the innate immunity’s cellular response to the site of antibody binding. In humans there are a range of Fc receptors including those for IgM, (Fc mu receptors), IgA (Fc alpha receptors), IgE (Fc epsilon receptors) and IgG (Fc gamma receptors). Although these all serve an important biological purpose it is Fc gamma receptors (FcgR or FcγR) that are of most interest in therapeutic antibody development as the majority of antibodies or related molecules in development are of the IgG subclass. For this reason, Gamma Proteins focuses on the supply of high-quality Fc gamma receptors. In humans there are five Fc gamma receptors: Fc gamma RI (FcgRI or CD64); Fc gamma RIIa (FcgRIIa or CD32a); Fc gamma RIIb (FcgRIIb or CD32b); Fc gamma RIIIa (FcgRIIIa or CD16a); and Fc gamma RIIIb (FcgRIIIb or CD16b). Gamma Proteins supplies the extra cellular domains (ECDs) for all the human Fc gamma receptors, including the polymorphic variants or allotypes for CD32a, CD16a and CD16b. All Fc gamma receptors are available in unconjugated or biotinylated formats.
